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Restylane® Cosmetic Filler
Darrick E. Antell, M.D., F.A.C.S.850 Park Avenue, New York, New York 10075


What is Restylane®?

Restylane® is a safe and natural cosmetic dermal filler that restores volume and fullness to the skin to correct moderate to severe facial wrinkles and folds, such as nasolabial folds.

What is Restylane® made of?

Restylane® is a cosmetic dermal filler composed of non-animal stabilized hyaluronic acid. Hyaluronic acid is a natural substance that already exists in the human body and is used to provide volume and fullness to the skin. The hyaluronic acid in Restylane® is a crystal-clear gel called NASHA™. NASHA is biodegradable and completely biocompatible with human hyaluronic acid.

What should patients do prior to treatment?

Restylane® requires no pretesting, but you should take a few precautions before being treated. One week prior to treatment with Restylane®, avoid taking St.John's Wort, high doses of Vitamin E supplements, aspirin, and other non-steroidal anti-inflammatory medications such as ibuprofen. These agents may increase bruising and bleeding at the injection site. Also, if you have previously suffered from facial cold sores, there is a risk that the needle punctures could contribute to another recurrence.

Is Restylane® safe?

Yes. Restylane® has been used by dermatologists and plastic surgeons since 1996 worldwide. Restylane® has a highly favorable safety profile. It's composed of non-animal stabilized hyaluronic acid. Hyaluronic acid is a substance found naturally in the human body. Restylane® is fully biocompatible. There is limited risk of animal-based disease transmission or development of allergic reactions to animal proteins. No allergy testing is required before use.* After your treatment, you might have some redness or swelling. This will normally last less than seven days. Sunbathing and cold outdoor activities should be avoided until any redness or swelling disappear. If you are pregnant, breastfeeding, or under 18, you shouldn't use Restylane®.*


  • The safety of Restylane® for use during pregnancy, in breastfeeding females or in patients under 18 years has not been established.
  • The safety of Restylane® in patients with increased susceptibility to keloid formation and hypertrophic scarring has not been studied. Restylane® should not be used in patients with known susceptibility to keloid formation or hypertrophic scarring.
  • The patient should be informed that he or she should minimize exposure of the treated area to excessive sun and UV lamp exposure and extreme cold weather until any initial swelling and redness has resolved.
  • If laser treatment, chemical peeling or any other procedure based on active dermal response is considered after treatment with Restylane® there is a possible risk of eliciting an inflammatory reaction at the implant site. This also applies if Restylane® is administered before the skin has healed completely after such a procedure. 

Can Restylane® be used anywhere on the face?

Restylane® has been used in more than 1.5 million treatments in over 60 countries to correct a variety of wrinkles. It is currently indicated in the U.S. for the treatment of moderate to severe facial wrinkles and folds, such as nasolabial folds.

How long does Restylane® last?

Restylane® can deliver long-lasting results. Studies have shown that Restylane® effects generally last for about six months. The unique NASHA™ technology helps maintain the cosmetic effect until the injected material is nearly gone.*

How often should I have Restylane® treatments done?

Having a follow-up treatment before the product has fully dissipated may enhance the lasting effect. Please be sure to consult your physician about recommendations for touch-up or follow-up treatments.

How is Restylane® different from BOTOX®?

Restylane® is a natural, cosmetic filler. In contrast, Botox is a drug that blocks nerve transmission and relaxes the underlying muscles. Many patients have been very pleased after receiving treatment with both products.

How is Restylane® different from bovine collagen?

Bovine collagen is derived from animals (cow) and requires an allergy test. Restylane® can be administered without pretesting, so no waiting is required. With Restylane® there is limited risk of animal-based disease transmission or allergic reaction.

Do the injections hurt?

Restylane® is injected directly into the skin in tiny amounts by an ultrafine needle, resulting in minimal discomfort. The procedure is simple and convenient, and results are practically instantaneous.* To optimize your comfort during the short procedure, your physician may anesthetize the treatment area.

The wait is over. Now that you have the answers to some important questions, why wait? Restylane® is a safe, natural formulation, so there are no delays for allergy testing prior to treatment. The simple procedure can be done during your lunch hour. And the effects can be seen shortly after your procedure.

How to get started?

Dr. Darrick E. Antell and his staff will be happy to discuss Restylane® (Injectable Filler) with you.  Please call for a private consultation or schedule an appointment online at our office.


Related Patient Testimonials*
* Patients individual results may vary.
  • Very happy with the service. The atmosphere in the office is warm and welcoming. Keep up the great job! Friendly front desk staff very important & not often found in Park Ave.
  • I have always appreciated the very professional service I have received from Dr. Antell and his staff. I can't think of anything that would improve upon the experiences I have already had.
*Disclaimer: The information contained on this website is intended to be purely educational in nature and does not create a physician-patient relationship with Darrick E. Antell, MD, FACS or any agent, servant or employee thereof. By no means should the information contained in this website be considered as a substitute for consultation with a qualified physician and it does not constitute a second opinion. This website and its contents do not represent or claim to provide the information needed for a patient to give his or her informed consent to any surgical procedure or are a reflection of individual patient results, as they may vary patient to patient. Individual results will vary and no guaranteed result is stated or implied by any photo use or any statement, testimonial, or video on this website. The results depicted in “before” and “after” pictures and stated by any “patient testimonial” illustrate results you may or may not achieve if you choose to have a cosmetic surgery procedure. Individual results may vary by patient. Please see our Notice of Privacy Practices.
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